The purpose of this research was to investigate and compare the effectiveness of additively manufactured and wrought cobalt-chromium (Co-Cr) alloy as a dental implant through a set of corrosion, immersion, and tribological behavior analyses using artificial saliva as electrolyte and lubricating medium. X-ray fluorescence and inductively coupled plasma atomic emission spectroscopy techniques were used for the elemental analysis of metal powder and wrought samples. Two types of CoCr alloys: CoCrMo and CoCrW were manufactured from Laser Powder Directed Energy Deposition (LP-DED) process. Fusayama-Meyer solution guidelines were followed when preparing the artificial saliva. Saliva with varying pH (4.9, 6.8, and 9) concentrations were used in open circuit potential and potentiodynamic polarization studies to examine the corrosive responses of the used alloy. The most corrosive media was selected for further testing based on the initial pilot experiments. With continuous immersion in the saliva solution for predetermined intervals, the impact of artificial saliva on the topographical characteristics of the Co-Cr samples was investigated. Utilizing ball-on-flat type reciprocating friction and wear testing with an AISI 52100 steel ball, tribological tests were performed with replicating contact conditions on implants under dry and saliva-lubricated circumstances. The wear volume and 3D profilometry of the wear track for flat and ball samples were using white light interferometry techniques. The wear mechanisms were analyzed by Scanning Electron Microscopy and the potentially developed tribo-films on contact surfaces were characterized by Energy-dispersive X-ray spectroscopy (EDS). Captured findings can play crucial role to provide new insights for dental prosthetics development using metal additive manufacturing techniques.